Agmatine, A Metabolite of Arginine, Improves Learning and Memory in Streptozotocin-Induced Alzheimer's Disease Model in Rats


Sirvanci-Yalabik M., Sehirli A. O. , Utkan T. , Arıcıoğlu F.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.26, ss.342-354, 2016 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 26
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5455/bcp.20161121125642
  • Dergi Adı: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
  • Sayfa Sayısı: ss.342-354

Özet

Objective: Agmatine, the decarboxylation product of arginine produced by arginine decarboxylase, is a novel neurotransmitter and exists in the mammalian brain. Agmatine has been reported to modulate cognitive functions, including learning and memory.