Agmatine, A Metabolite of Arginine, Improves Learning and Memory in Streptozotocin-Induced Alzheimer's Disease Model in Rats
KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.26, ss.342-354, 2016 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 26
- Basım Tarihi: 2016
- Doi Numarası: 10.5455/bcp.20161121125642
- Dergi Adı: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.342-354
- Anahtar Kelimeler: agmatine, streptozotocine, Alzheimer's disease, passive avoidance, Morris water maze, PREFRONTAL CORTICAL MORPHOLOGY, NITRIC-OXIDE SYNTHASE, OXIDATIVE STRESS, ENDOGENOUS AGMATINE, CEREBRAL-ISCHEMIA, HIPPOCAMPAL, PROTECTS, BRAIN, GLUTAMATE, NMDA
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Kocaeli Üniversitesi Adresli: Evet
Özet
Objective: Agmatine, the decarboxylation product of arginine produced by arginine decarboxylase, is a novel neurotransmitter and exists in the mammalian brain. Agmatine has been reported to modulate cognitive functions, including learning and memory.