Effective treatment of hereditary angioedema with fresh frozen plasma in an emergency department


Pekdemir M. , Ersel M., Aksay E., Yanturalı S., Akturk A. , Kiyan S.

JOURNAL OF EMERGENCY MEDICINE, cilt.33, ss.137-139, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 33
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.jemermed.2007.02.024
  • Dergi Adı: JOURNAL OF EMERGENCY MEDICINE
  • Sayfa Sayıları: ss.137-139

Özet

Hereditary angioedema (HAE) is a rarely seen disorder of C1 inhibitor (C1-INH) deficiency usually manifested by non-pruritic swelling of the skin. Acute exacerbations are not sensitive to conventional medications, and Cl-esterase inhibitor concentrates are recommended as the first-line therapy. However, fresh frozen plasma is the main treatment alternative in many centers due to the lack of C1-esterase inhibitor concentrates. In this report, we present 3 patients with acute exacerbations of hereditary angioedema who were effectively and safely treated with fresh frozen plasma. (C) 2007 Elsevier Inc.