Effects of agmatine on cognitive functions during vascular dementia in biological aging through eNOS and BDNF expression

Bağci, Bulent; Utkan, TİJEN; Yazır, YUSUFHAN; Arıcıoğlu, Feyza; Ozturk, Gokce; Sarioglu, Yusuf

doi:10.1080/24750573.2017.1309090

Effects of agmatine on cognitive functions during vascular dementia in biological aging through eNOS and BDNF expression

Atıf İçin Kopyala

Bağci B., Utkan T., Yazır Y., Arıcıoğlu F., Ozturk G. S., Sarioglu Y.

PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, cilt.27, ss.106-115, 2017 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 27
Basım Tarihi: 2017
Doi Numarası: 10.1080/24750573.2017.1309090
Dergi Adı: PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.106-115
Kocaeli Üniversitesi Adresli: Evet

Özet

Objective: Biological aging has been recognized to cause impairment of memory and the development of vascular dementia. Based on our previous work, agmatine has been shown to have a beneficial effect and might have therapeutic potential on cognitive functions, including learning and memory. The aim of the present study was to examine the possible effect of agmatine on biological aging-induced vascular endothelial dysfunction and associated dementia in rats.