Effects of agmatine on cognitive functions during vascular dementia in biological aging through eNOS and BDNF expression

Bağci, Bulent; Utkan, TİJEN; Yazır, YUSUFHAN; Arıcıoğlu, Feyza; Ozturk, Gokce; Sarioglu, Yusuf

doi:10.1080/24750573.2017.1309090

Effects of agmatine on cognitive functions during vascular dementia in biological aging through eNOS and BDNF expression

Bağci B., Utkan T., Yazır Y., Arıcıoğlu F., Ozturk G. S., Sarioglu Y.

PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, vol.27, pp.106-115, 2017 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 27
Publication Date: 2017
Doi Number: 10.1080/24750573.2017.1309090
Journal Name: PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.106-115
Open Archive Collection: AVESIS Open Access Collection
Kocaeli University Affiliated: Yes

Abstract

Objective: Biological aging has been recognized to cause impairment of memory and the development of vascular dementia. Based on our previous work, agmatine has been shown to have a beneficial effect and might have therapeutic potential on cognitive functions, including learning and memory. The aim of the present study was to examine the possible effect of agmatine on biological aging-induced vascular endothelial dysfunction and associated dementia in rats.