Severe jaundice due to coexistence of Dubin-Johnson syndrome and hereditary spherocytosis: A case report

Korkmaz U., Duman A. E., Koc D. O., Gurbuz Y., Dindar G., Ensaroglu F., ...Daha Fazla

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.22, sa.4, ss.422-425, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.4318/tjg.2011.0261
  • Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.422-425
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Dubin-Johnson syndrome is a chronic, benign, intermittent jaundice, mostly of conjugated hyperbilirubinemia. The level of bilirubin is not expected to be more than 20 mg/dl in this syndrome. In this article, we report a patient who was evaluated for hyperbilirubinemia and liver function test abnormalities and diagnosed with Dubin-Johnson syndrome coexisting with hereditary spherocytosis. We suggest that other diseases should be investigated if patients with Dubin-Johnson syndrome present with severe hyperbilirubinemia. Dubin-Johnson syndrome accompanied by hemolytic diseases might also have high coproporphyrin levels (as in Rotor's syndrome) than expected in pure Dubin-Johnson syndrome.