ANNALS OF OPHTHALMOLOGY, vol.33, no.1, pp.43-47, 2001 (SCI-Expanded)
In a double-blind study, room-temperature lidocaine was injected randomly, into 1 eyelid of 40 patients during facial anesthesia. Tire other eyelid of the same eye received injection of warm lidocaine (group 1) or bicarbonate-buffered lidocaine (group 2). Based on a pain scale, warming or buffering lidocaine did not significantly reduce the amount of infiltration pain. Buffering lidocaine was effective in reducing the quality of pain, as judged by the patient's report of dominant pain.