Akademik Veri Yönetim Sistemi
NAURYZ 5TH INTERNATIONAL CONFERENCE ON SCIENTIFIC RESEARCH, Ankara, Türkiye, 10 - 12 Nisan 2022, cilt.1, ss.34-39
Endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) is becoming the standard tool for
obtaining cell block from pancreatic mass, which may also contribute to immunohistochemical study.
However, in some cases, a single cytological or histological evaluation may not be sufficient for
diagnosis. In this study, I aimed to evaluate the diagnostic value of EUS-FNA for solid pancreatic
masses.
Patients who underwent EUS-FNA-guided procedure for pancreatic mass between June 2021 and
January 2022 were included in the study retrospectively. Diff-Quick and Papanicolaou staining were
applied to the obtained smears. Cell blocks were tried to be obtained and immunohistochemical stainings
were stained for the diagnosis of these blocks and all were analyzed.
There were 27 patients (14 women and 13 men; age ranges 27-92) who had a pancreatic mass and
underwent EUS-FNA. When the aspiration and cell blocks obtained from four of the 27 patients were
examined, they were considered non-diagnostic and could not be diagnosed with malignancy, since they
contained hemorrhagic and fibrinous material. 21 patients were diagnosed with malignancy. While 3 of
them were neuroendocrine tumors, 18 of them were adenocarcinomas. Immunohistochemical staining
was performed on the cell blocks of 3 cases for the diagnosis of neuroendocrine tumors. 2 patients were
diagnosed as benign. One was diagnosed with pancreatitis and the other with pseudocyst.
In fine-needle aspirations for pancreatic masses, correct needle selection and material acquisition with
the correct technique (and subsequently on-site cytological evaluation) cause an increase in aspiration
adequacy rates. And thus, the rate of correct diagnosis to the patient increases considerably. The
experience of the pathologist and gastroenterologist is also very important in these cases.