Evaluation of prophylactic and therapeutic effects of ruscogenin on acute radiation proctitis: an experimental rat model

Yavuz, Erkan; Karagulle, Onur; Ercan, Gulcin; Celik, Atilla; Yigitbas, Hakan; Bayrak, BÜŞRA; Tartar, Rumeysa; Kusaslan, Ramazan; Altinel, Yuksel; Gulcicek, Osman

doi:10.4174/astr.2018.94.4.174

Evaluation of prophylactic and therapeutic effects of ruscogenin on acute radiation proctitis: an experimental rat model

Yavuz E., Karagulle O. O., Ercan G., Celik A., Yigitbas H., Bayrak B., ...Daha Fazla

ANNALS OF SURGICAL TREATMENT AND RESEARCH, cilt.94, sa.4, ss.174-182, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 94 Sayı: 4
Basım Tarihi: 2018
Doi Numarası: 10.4174/astr.2018.94.4.174
Dergi Adı: ANNALS OF SURGICAL TREATMENT AND RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.174-182
Anahtar Kelimeler: Ruscogenin, Proctitis, Radiation, PELVIC RADIOTHERAPY, INJURY, CYTOKINES, MECHANISM
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Kocaeli Üniversitesi Adresli: Evet

Özet

Purpose: Radiation proctitis (RP) is inflammation and damage to the rectum, manifested secondary to ionizing radiation utilized for treatment. In this study, we evaluated the anti-inflammatory therapeutical and protective effects of ruscogenin in a model of acute RP.