Evaluation of prophylactic and therapeutic effects of ruscogenin on acute radiation proctitis: an experimental rat model

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Yavuz E., Karagulle O. O., Ercan G., Celik A., Yigitbas H., Bayrak B., ...More

ANNALS OF SURGICAL TREATMENT AND RESEARCH, vol.94, no.4, pp.174-182, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 94 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.4174/astr.2018.94.4.174
  • Journal Name: ANNALS OF SURGICAL TREATMENT AND RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.174-182
  • Keywords: Ruscogenin, Proctitis, Radiation, PELVIC RADIOTHERAPY, INJURY, CYTOKINES, MECHANISM
  • Kocaeli University Affiliated: Yes

Abstract

Purpose: Radiation proctitis (RP) is inflammation and damage to the rectum, manifested secondary to ionizing radiation utilized for treatment. In this study, we evaluated the anti-inflammatory therapeutical and protective effects of ruscogenin in a model of acute RP.