Evaluation of prophylactic and therapeutic effects of ruscogenin on acute radiation proctitis: an experimental rat model

Yavuz, Erkan; Karagulle, Onur; Ercan, Gulcin; Celik, Atilla; Yigitbas, Hakan; Bayrak, BÜŞRA; Tartar, Rumeysa; Kusaslan, Ramazan; Altinel, Yuksel; Gulcicek, Osman

doi:10.4174/astr.2018.94.4.174

Evaluation of prophylactic and therapeutic effects of ruscogenin on acute radiation proctitis: an experimental rat model

Yavuz E., Karagulle O. O., Ercan G., Celik A., Yigitbas H., Bayrak B., ...More

ANNALS OF SURGICAL TREATMENT AND RESEARCH, vol.94, no.4, pp.174-182, 2018 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 94 Issue: 4
Publication Date: 2018
Doi Number: 10.4174/astr.2018.94.4.174
Journal Name: ANNALS OF SURGICAL TREATMENT AND RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.174-182
Keywords: Ruscogenin, Proctitis, Radiation, PELVIC RADIOTHERAPY, INJURY, CYTOKINES, MECHANISM
Open Archive Collection: AVESIS Open Access Collection
Kocaeli University Affiliated: Yes

Abstract

Purpose: Radiation proctitis (RP) is inflammation and damage to the rectum, manifested secondary to ionizing radiation utilized for treatment. In this study, we evaluated the anti-inflammatory therapeutical and protective effects of ruscogenin in a model of acute RP.