Kocaeli Tıp Dergisi, cilt.10, sa.2, ss.111-118, 2021 (Hakemli Dergi)
INTRODUCTION: Our study aims to evaluate the diagnostic performances of Dynamic Contrast-En-hanced Magnetic Resonance Perfusion Imaging (DCE-MRPI) and T2 relaxation (T2 Mapping) parameters in the differentiation of benign and malignant soft tissue masses. METHODS: The study included 36 patients with 36 soft tissue masses (17 malignant and 19 benign). Imaging was performed using a 3 Tesla MRI, T2 perfusion and T2 relaxation studies were performed and Index, Negative Integral (NI), Mean Transit Time (MTT), Time to Peak (TTP), Time of Arrival (T0), and mean value of T2 relaxation time were calculated. Then, these parameters were compared between benign and malignant lesions. RESULTS: The differences of the maximum dimension of the lesions and NI values between benign and malignant masses were found statistically significant (p = 0.01 and p = 0.001 respectively). There was a statistically significant relationship between the presence of peritumoral edema and malignancy (p =0.05). DISCUSSION AND CONCLUSION: For the differentiation of benign from malignant soft tissue masses NI value may provide added information, when combined with conventional MRI and clinical findings. T2 relaxation times were not helpful in this regard due to significant overlap between benign and malig nant masses.