Selective nuclear factor kappa-B inhibitors, pyrolidium dithiocarbamate and sulfasalazine, prevent the nephrotoxicity induced by gentamicin


Tugcu V., Ozbek E., Tasci A. I., Kemahli E., Somay A., Bas M., ...Daha Fazla

BJU INTERNATIONAL, cilt.98, sa.3, ss.680-686, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 98 Sayı: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1111/j.1464-410x.2006.06321.x
  • Dergi Adı: BJU INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.680-686
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

OBJECTIVE To investigate the effect of selective nuclear factor kappa-B (NF kappa-B) inhibitors, pyrolidium dithiocarbamate (PD) and sulfasalazine (SZ) on renal tubular necrosis and inducible nitric oxide synthase (iNOS) and NF kappa-B expression induced by gentamicin in rats.