Selective nuclear factor kappa-B inhibitors, pyrolidium dithiocarbamate and sulfasalazine, prevent the nephrotoxicity induced by gentamicin

Tugcu V., Ozbek E., Tasci A. I. , Kemahli E., Somay A., Bas M., ...Daha Fazla

BJU INTERNATIONAL, cilt.98, ss.680-686, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier


OBJECTIVE To investigate the effect of selective nuclear factor kappa-B (NF kappa-B) inhibitors, pyrolidium dithiocarbamate (PD) and sulfasalazine (SZ) on renal tubular necrosis and inducible nitric oxide synthase (iNOS) and NF kappa-B expression induced by gentamicin in rats.