Evaluation of vitamin D receptor gene polymorphisms in patients with differentiated thyroid carcinomas and nodular goiter

Gunes A., Yazicioglu M. B., Tiryaki C., Uren N., Ergül E., Simsek T., ...Daha Fazla

MINERVA ENDOCRINOLOGY, cilt.46, sa.3, ss.317-324, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.23736/s2724-6507.20.03160-0
  • Dergi Adı: MINERVA ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.317-324
  • Anahtar Kelimeler: Thyroid neoplasms, Goiter, Goiter, nodular, DRIP, VDR interacting protein complex, VDR GENE, CANCER, RISK, TAQI, 1-ALPHA-HYDROXYLASE, STRATIFICATION, ASSOCIATION, ULTRASOUND, EXPRESSION, STATE
  • Kocaeli Üniversitesi Adresli: Evet

Özet

BACKGROUND: The role of vitamin D has previously been determined in autoimmune and malignant thyroid diseases. We aimed to identify the haplotype distribution of single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene, which has been suggested to play a role in the pathogenesis of differentiated thyroid cancers and benign thyroid diseases.