Evaluation of vitamin D receptor gene polymorphisms in patients with differentiated thyroid carcinomas and nodular goiter

Gunes A., Yazicioglu M. B. , Tiryaki C., Uren N., Ergül E. , Simsek T. , ...More

MINERVA ENDOCRINOLOGY, vol.46, no.3, pp.317-324, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.23736/s2724-6507.20.03160-0
  • Title of Journal : MINERVA ENDOCRINOLOGY
  • Page Numbers: pp.317-324
  • Keywords: Thyroid neoplasms, Goiter, Goiter, nodular, DRIP, VDR interacting protein complex, VDR GENE, CANCER, RISK, TAQI, 1-ALPHA-HYDROXYLASE, STRATIFICATION, ASSOCIATION, ULTRASOUND, EXPRESSION, STATE

Abstract

BACKGROUND: The role of vitamin D has previously been determined in autoimmune and malignant thyroid diseases. We aimed to identify the haplotype distribution of single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene, which has been suggested to play a role in the pathogenesis of differentiated thyroid cancers and benign thyroid diseases.