Evaluation of vitamin D receptor gene polymorphisms in patients with differentiated thyroid carcinomas and nodular goiter

Gunes A., Yazicioglu M. B., Tiryaki C., Uren N., Ergül E., Simsek T., ...More

MINERVA ENDOCRINOLOGY, vol.46, no.3, pp.317-324, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.23736/s2724-6507.20.03160-0
  • Journal Name: MINERVA ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.317-324
  • Keywords: Thyroid neoplasms, Goiter, Goiter, nodular, DRIP, VDR interacting protein complex, VDR GENE, CANCER, RISK, TAQI, 1-ALPHA-HYDROXYLASE, STRATIFICATION, ASSOCIATION, ULTRASOUND, EXPRESSION, STATE
  • Kocaeli University Affiliated: Yes

Abstract

BACKGROUND: The role of vitamin D has previously been determined in autoimmune and malignant thyroid diseases. We aimed to identify the haplotype distribution of single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene, which has been suggested to play a role in the pathogenesis of differentiated thyroid cancers and benign thyroid diseases.