The relationship between genetic susceptibility to head and neck cancer with the expression of common fragile sites


Egeli U., Ozkan L., Tunca B., Kahraman S., Cecener G., Ergul E., ...More

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, vol.22, no.6, pp.591-598, 2000 (SCI-Expanded) identifier identifier

Abstract

Background. Numerous studies have recently been conducted to investigate genetic mechanisms in cancer causes and pathogenesis. Some of these studies have shown that there were certain specific chromosomal defects in normal cells of cancer patients and in their first-degree relatives. It was suggested that these individuals were susceptible to cancer development when compared with people without these defects.