Prevention of Epineural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin

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Vural E., Yilmaz M., Ilbay K., İlbay G.

TURKISH NEUROSURGERY, vol.26, no.2, pp.291-296, 2016 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.5137/1019-5149.jtn.7705-12.1
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.291-296
  • Keywords: Daunorubicin, Mitomycin C, Perineural fibrosis, Peripheral nerve, Rat, Topical, PERIPHERAL-NERVE SURGERY, STRABISMUS SURGERY, SCAR FORMATION, CAPSULE FIBROBLASTS, TOPICAL APPLICATION, ADHESIONS, SUBCONJUNCTIVAL, TRABECULECTOMY, LAMINECTOMY, 5-FLUOROURACIL
  • Open Archive Collection: AVESIS Open Access Collection
  • Kocaeli University Affiliated: Yes

Abstract

AIM: Epineural adhesion after peripheral nerve surgery is common. The purpose of this study was to evaluate the macroscopic and histopathologic effects of topical mitomycin C and daunorubicin on epineural scar formation.