Infliximab prevents dysfunction of the vas deferens by suppressing inflammation and oxidative stress in rats with chronic stress


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Demirtaş Şahin T. , Gocmez S. S. , Duruksu G. , Yazir Y. , Utkan T.

LIFE SCIENCES, vol.250, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 250
  • Publication Date: 2020
  • Doi Number: 10.1016/j.lfs.2020.117545
  • Title of Journal : LIFE SCIENCES

Abstract

Aims: Chronic stress leads to the development of male sexual problems such as ejaculatory dysfunctions. The rhythmic contractions of vas deferens (VD) play an important role on the ejaculatory process. In the current study, we investigated whether infliximab (IFX) treatment has any beneficial effects on possible alterations in contractility of VD obtained from rats exposed to unpredictable chronic mild stress (UCMS).