Beneficial effects of Oltipraz, nuclear factor - erythroid-2-related factor 2 (Nrf2), on renal damage in unilateral ureteral obstruction rat model

Polat E. C., Besiroglu H., Ozcan L., Otunctemur A., Eruyar A. T., Somay A., ...More

INTERNATIONAL BRAZ J UROL, vol.44, no.6, pp.1243-1251, 2018 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 44 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.1590/s1677-5538.ibju.2018.0232
  • Journal Name: INTERNATIONAL BRAZ J UROL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1243-1251
  • Keywords: Oltipraz [Supplementary Concept], Renal Insufficiency, Ureter, EPITHELIAL-MESENCHYMAL TRANSITION, FIBROSIS, KIDNEY, ANTIOXIDANT, STRESS, INJURY, BETA
  • Kocaeli University Affiliated: Yes

Abstract

Introduction: We investigated whether Oltipraz (OPZ) attenuated renal fibrosis in a unilateral ureteral obstruction (UUO) rat model.