Turkish Archives of Pediatr, cilt.2, sa.59, ss.270-276, 2024 (Hakemli Dergi)
ABSTRACT
Objective: Fetal growth is known to be affected by ethnic and environmental factors; therefore,
intrauterine growth references for each community vary and need to be determined individually. This study aimed to construct intrauterine growth references for Turkish infants.
Materials and Methods: This prospective, multicenter, cross-sectional study was performed in
collaboration with the Turkish Ministry of Health and the Turkish Neonatology Society, in coordination with Mersin University. The study included 33 healthcare centers from all regions of
Türkiye. The study included singleton infants who were born alive at 24-42 weeks of gestation.
Weight, length, and head circumference were measured within the first 4 hours of delivery. The
Lambda–Mu–Sigma method and penalized likelihood were used to establish the curves and
construct percentiles.
Results: In all, data from 10 286 infants were analyzed and 552 cases that did not meet the
inclusion criteria were excluded. The intrauterine growth curves and tables for Turkish infants
were constructed using the data for 9734 singleton infants born at 24-42 weeks of gestation.
Conclusion: To the best of our knowledge this is the first study to establish intrauterine growth
references for Turkish infants, based on a cohort of infants from all regions of Türkiye. Using
these new references, the intrauterine growth of Turkish infants and postnatal growth of those
born prematurely can be followed-up more effectively, and it will be possible to more accurately determine if Turkish infants are small for gestational age or large for gestational age.
Keywords: Infants, intrauterine growth references, large for gestational age, small for gest