Central pontine and extrapontine myelinolysis owing to disequilibrium syndrome


Aydin O., Uner C., Senbil N., Bek K. , Erdogan O., Gurer Y.

JOURNAL OF CHILD NEUROLOGY, cilt.18, ss.292-296, 2003 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 18 Konu: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1177/08830738030180040701
  • Dergi Adı: JOURNAL OF CHILD NEUROLOGY
  • Sayfa Sayısı: ss.292-296

Özet

Neurologic disorders can be seen in patients with end-stage renal failure owing to complications of hemodialysis or peritoneal dialysis. The disequilibrium syndrome can be seen, usually soon after or toward the end of dialysis. We report a patient with central pontine and extrapontine myelinolysis owing to disequilibrium syndrome. The patient had depressed consciousness, agitation, tremor, stupor, and hyperactive deep tendon reflexes toward the end of the second peritoneal dialysis. A brain computed tomographic (CT) scan showed hypodense lesions in pontine and extrapontine locations without radiocontrast medium enhancement. After 2 days, the patient had only minimal memory deficits. A control brain CT scan 1 week later showed a decrease of the lesions in central pontine and extrapontine locations. Central pontine and extrapontine myelinolysis should be suspected and investigated in the acute neurologic disorders of dialysis patients. (J Child Neurol 2003;18:292-296).