Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.39, sa.5, ss.257-264, 2011 (Scopus)
Aim: We investigated the impact of anesthetic depth by bispectral index (BIS) monitorization on anesthetic drug usage, eye opening and extubation time after anesthesia on patients who are undergoing transsphenoidal hypophysectomy under general anesthesia. Material and Method: After approval of Kocaeli University Ethics Committee 60 ASA II-III patients aged 18-60 years who were scheduled for transsphenoidal hypophysectomy were enrolled in this prospective randomized study. The patients were divided into 2 groups as Groups I, and II which included patients who were followed-up with or without BIS monitorization, respectively. After routine monitorization; Group I was monitorized by BIS before the induction of anasthesia. The same anesthesia technique was administered to all of the patients. In Group I, concentration of sevoflurane was regulated according to the BIS ratio (50-60). In Group II sevoflurane concentration was 2 %. Measurements: The parameters were recorded preoperatively, after induction, and at 5., 10., and 15. minutes post- intubation, and also every 15 minutes during the operation. The administration of the volatile agent was terminated, after completion of the surgical procedure. The period from the cessation of the anesthetic drugs up to the extubation was defined as the extubation time, and the time between verbal stimulus, and eye-opening was assessed as eye opening time. Besides total usage of sevoflorane and remifentanyl and value of the MAC were recorded at end of the operation. Results: Age, body weights, gender and total usage of the remifentanyl were similar in both groups. When compared to Group II, in Group I there was a significant decrease in the amount of sevoflurane and MAC (p<0, 05). There were no significant differences between the groups as for extubation and eye- opening times, and hemodynamic responses (mean arterial pressures, and heart rates). Conclusion: In patients undergoing general anesthesia. who are being monitored for anesthetic depth with BIS the consumption of volatile agent is reduced.