The stereochemistry of the hydroboration of 2-and 3-methylene-5 alpha-androstanes

Al-Footy K., Hanson J., UYANIK C.

JOURNAL OF CHEMICAL RESEARCH-S, sa.5, ss.304-305, 1999 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: Sayı: 5
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1039/a809761e
  • Dergi Adı: JOURNAL OF CHEMICAL RESEARCH-S
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.304-305
  • Kocaeli Üniversitesi Adresli: Evet

Özet

The exo facial selectivity in the hydroboration of 2-, 3- and 4-methylene-5 alpha-androstanes is rationalized in terms of the easier steric access and a hyperconjugative interaction of the alkene with the adjacent axial C-H bonds enhancing the electron density on one face of the alkene.