Antinociception induced by verapamil and chloramphenicol in mice


Yıldıran G., Ulak G. , Utkan G. , Göldeli E., Gacar N., Erden F.

BIOLOGY OF THE NEONATE, cilt.72, ss.28-31, 1997 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 72
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1159/000244463
  • Dergi Adı: BIOLOGY OF THE NEONATE
  • Sayfa Sayısı: ss.28-31

Özet

The analgesic effects of verapamil, a calcium channel blocker, and chloramphenicol, a phenicolated antibiotic, were compared using the test of acetic-acid-induced writhing and the hot-plate test in mice. The results suggest that both drugs have antinociceptive properties comparable to salicylate analgesia. No significant difference was found between verapamil- and chloramphenicol-induced analgesia (p < 0.05).