Esophageal smooth muscle reactivity is impaired in chronic reflux esophagitis by both receptor- and nonreceptor-mediated mechanisms

Tuğtepe H., Tugay M., Bozkurt S., Yildiz F., Utkan T., Yegen B. C., ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.42, ss.641-646, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.jpedsurg.2006.12.048
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.641-646
  • Anahtar Kelimeler: gastroesophageal reflux, smooth muscle, carbachol, serotonin, in vitro, esophagus, GASTROESOPHAGEAL-REFLUX, MOTOR ABNORMALITIES, CIRCULAR MUSCLE, DISEASE, RAT, MOTILITY, PH, FUNDOPLICATION, DYSFUNCTION, RELAXATION
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Aim: Esophagitis is associated with an impaired esophageal peristalsis. A few studies have been aimed at understanding the pathophysiology of abnormal peristaltic activity. The mechanism of impaired esophageal smooth muscle reactivity in the chronic gastroesophageal reflux (GER) model is investigated in vitro for the first time.