Effect of cholecalciferol on local arterial stiffness and endothelial dysfunction in children with chronic kidney disease
PEDIATRIC NEPHROLOGY, vol.31, no.2, pp.267-277, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 31 Issue: 2
- Publication Date: 2016
- Doi Number: 10.1007/s00467-015-3220-5
- Journal Name: PEDIATRIC NEPHROLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.267-277
- Keywords: Chronic kidney disease, 25-hydroxyvitamin D3, Children, Flow-mediated dilatation, Arterial stiffness, VITAMIN-D DEFICIENCY, STAGE RENAL-DISEASE, LEFT-VENTRICULAR HYPERTROPHY, CARDIOVASCULAR MORTALITY, HEMODIALYSIS-PATIENTS, MINERAL METABOLISM, HYPERHOMOCYSTEINEMIA, DIALYSIS, IMPACT, ADULTS
- Kocaeli University Affiliated: Yes
Abstract
As cardiovascular factors are the leading cause of mortality in chronic kidney disease (CKD) and as vitamin D deficiency is prevalent in this population, we aimed to examine the effect of oral cholecalciferol on cardiac parameters and biomarkers for endothelial cell activation in children with CKD.