Effect of cholecalciferol on local arterial stiffness and endothelial dysfunction in children with chronic kidney disease

AYTAÇ M. B., Deveci M., BEK K., Kayabey O., Ekinci Z.

PEDIATRIC NEPHROLOGY, vol.31, no.2, pp.267-277, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.1007/s00467-015-3220-5
  • Journal Name: PEDIATRIC NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.267-277
  • Keywords: Chronic kidney disease, 25-hydroxyvitamin D3, Children, Flow-mediated dilatation, Arterial stiffness, VITAMIN-D DEFICIENCY, STAGE RENAL-DISEASE, LEFT-VENTRICULAR HYPERTROPHY, CARDIOVASCULAR MORTALITY, HEMODIALYSIS-PATIENTS, MINERAL METABOLISM, HYPERHOMOCYSTEINEMIA, DIALYSIS, IMPACT, ADULTS
  • Kocaeli University Affiliated: Yes

Abstract

As cardiovascular factors are the leading cause of mortality in chronic kidney disease (CKD) and as vitamin D deficiency is prevalent in this population, we aimed to examine the effect of oral cholecalciferol on cardiac parameters and biomarkers for endothelial cell activation in children with CKD.