Effect of Smoking on Rat Basilar Artery: Correlation with Inducible Nitric Oxide Synthase and Endothelin Converting Enzyme-1

Koc K., ANIK İ. , Bozkurt S. U. , Ercin C., CEYLAN S.

TURKISH NEUROSURGERY, vol.19, no.4, pp.393-399, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2009
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.393-399


AIM: Smoking is an extremely important risk factor for subarachnoid hemorrhage and seems to increase rupture risk of unruptured aneurysms by accelerating their growth rate. The aim of the study was to investigate the effect of smoking on the luminal diameter with wall thicknesses of rat basilar arteries and to detect alterations of inducible nitric oxide synthase and endothelin-converting enzyme -1 in the endothelial cells.