Genetic evidence for PLASMINOGEN as a shared genetic risk factor of coronary artery disease and periodontitis.


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Schaefer A. S., Bochenek G., Jochens A., Ellinghaus D., Dommisch H., Guezeldemir-Akcakanat E., ...Daha Fazla

Circulation. Cardiovascular genetics, cilt.8, sa.1, ss.159-67, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1161/circgenetics.114.000554
  • Dergi Adı: Circulation. Cardiovascular genetics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.159-67
  • Anahtar Kelimeler: coronary artery disease, genetic association studies, periodontitis, plasminogen, GENOME-WIDE ASSOCIATION, SUSCEPTIBILITY LOCUS, TGF-BETA, ACTIVATION, ATHEROSCLEROSIS, INFLAMMATION, REPLICATION, 9P21.3, FORMS
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Background-Genetic studies demonstrated the presence of risk alleles in the genes ANRIL and CAMTA1/VAMP3 that are shared between coronary artery disease (CAD) and periodontitis. We aimed to identify further shared genetic risk factors to better understand conjoint disease mechanisms.