Synthesis and Characterization of Bioactive Glass Material by Hydrothermal Assisted Sol Gel Method

2nd European Congress on Advanced Nanomaterials and Nanotechnology, Rome, İtalya, 17 - 18 Kasım 2025, ss.12-13, (Özet Bildiri)

In this study, a hydrothermal-assisted sol–gel method was

employed to synthesize bioactive glass with the nominal molar

composition of 60SiO₂-36CaO-4P₂O₅ (mol%). The hydrothermal

system played a crucial role in accelerating the sol-to-gel

transition, thereby significantly reducing the overall processing

time compared to conventional sol-gel methods. This approach

offers a more efficient route for the production of bioactive glass,

which is known for its excellent bioactivity and biocompatibility,

particularly in bone tissue engineering applications.

Following the synthesis, the obtained gel-derived bioactive glass

powders were subjected to calcination to remove organic residues

and improve the structural stability. The calcined powders were

then extensively characterized using various analytical techniques.

X-ray diffraction (XRD) was performed to investigate the

crystallographic structure of the glass, and the results confirmed

the amorphous nature of the material. Thermal behavior and phase

transformations were studied by differential thermal analysis

(DTA) and thermogravimetric analysis (TGA), which provided

insights into the thermal stability and decomposition patterns of

the synthesized powders. Fourier-transform infrared spectroscopy

(FTIR) was utilized to identify the functional groups and confirm

the formation of silicate networks typical of bioactive glasses.

Furthermore, scanning electron microscopy (SEM) was employed

to examine the morphology and particle size distribution of the

glass powders, revealing a homogenous structure with nanoscale

features. To evaluate the in vitro bioactivity, the synthesized

bioactive glass powders were immersed in simulated body

fluid (SBF) under physiological conditions. The formation of

a hydroxyapatite-like layer on the surface of the glass particles

after immersion confirmed their bioactivity and potential for

bone-bonding applications. Overall, the study demonstrates that

the hydrothermal-assisted sol–gel method is an effective and

time-efficient technique for the synthesis of amorphous bioactive

glass with promising physicochemical and biological properties.

This method can serve as a valuable alternative to conventional

synthesis routes for the development of next-generation bioactive materials in biomedical applications.