Effect of Leflunomide Use on <SUP>68</SUP>Ga-DOTATATE Biodistribution in a Case With Neuroendocrine Tumor
CLINICAL NUCLEAR MEDICINE, cilt.48, sa.2, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Editöre Mektup
- Cilt numarası: 48 Sayı: 2
- Basım Tarihi: 2023
- Doi Numarası: 10.1097/rlu.0000000000004517
- Dergi Adı: CLINICAL NUCLEAR MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Kocaeli Üniversitesi Adresli: Hayır
Özet
A 58-year-old man who underwent surgery for a well-differentiated neuroendocrine tumor of pancreatic origin was evaluated with Ga-68-DOTATATE PET/CT imaging in the follow-up period. After PET/CT findings consistent with disease remission, the patient was started on leflunomide treatment with the diagnosis of rheumatoid arthritis. The patient received leflunomide for 6 months. Then, Ga-68-DOTATATE PET/CT scan was repeated to evaluate the primary disease outcome. Besides the disease remission, we also observed alterations in DOTATATE uptakes of some tissues and organs. In this case, we present the changes in Ga-68-DOTATATE PET/CT scan findings after leflunomide use.