Hypoalbuminemia Leads to An Increased Risk Of Mortality And Re-Operation Within 3-Months In Patients 75< Years Of Age After Surgery For Hip Fractures


Kurtoglu A., Sukur E., Kochai A., ÖZTAŞ ŞÜKÜR N. E., Oz I., Keskin D., ...Daha Fazla

PROGRESS IN NUTRITION, cilt.23, sa.4, 2021 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.23751/pn.v23i4.12175
  • Dergi Adı: PROGRESS IN NUTRITION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Background: The focus of this study is to ascertain a baseline nutritional level of adults 75 years old who are hospitalized for hip fracture surgery, and to assess the effects on the mortality rates and post-operative complications that require re-operation within 3 months of the initial surgery. Material and Methods: A total of 240 patients having surgery for fractured hips during 2017-2019 were identified. Patients' characteristics, including pre-operative laboratory findings, complications and reoperation rates were assessed. Multivariate logistic regression analysis was used to establish the effect of hypoalbuminemia and total lymphocyte count on the rates of 3-month post-operative complications, re-operation and mortality. Results: Among patients studied, 153 had hypoalbuminemia (albumin levels <3.5 g/dL), and 87 showed normal albumin levels (albumin levels >= 3.5 g/dL). Patients in the hypoalbuminemia group were likely to be functionally dependent (p = 0.002) and had higher Charlson comorbidity scores (p = 0.006) than their counterparts. The American Society of Anesthesiologists score and albumin levels were significant predictors of re-operation (p = 0.013, p = 0.039). The increase in age by 1 year, albumin level <3.5 g/dL, and lymphocyte count <1500 cells/mm(3) were associated with increased mortality rates (p = 0.012, p = 0.004, p = 0.002). Conclusion: Malnutrition is high in patients with hip fractures. In this study, hypoalbuminemia and lymphocyte count (<1500 cells/mm(3)) were directly associated with post-operative mortality rates and complications that required re-operation within 3 months of initial surgery.