Comparison of hyperbaric oxygen versus iloprost treatment in an experimental rat central retinal artery occlusion model


KARAMAN S., ÖZKAN B., YAZIR Y., Yardimoglu M., GÖK M., KARA O., ...More

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, vol.254, no.11, pp.2209-2215, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 254 Issue: 11
  • Publication Date: 2016
  • Doi Number: 10.1007/s00417-016-3444-5
  • Journal Name: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2209-2215
  • Keywords: Retinal artery occlusion, Hyperbaric oxygen therapy, Iloprost, Ischemia-reperfusion injury, ISCHEMIA-REPERFUSION INJURY, CRITICAL LIMB ISCHEMIA, SPINAL-CORD ISCHEMIA, IN-VIVO EVALUATION, RABBIT MODEL, HYPERTENSION, DISEASE, ANALOG
  • Kocaeli University Affiliated: Yes

Abstract

Central retinal artery occlusion (CRAO) is one of the serious ophthalmological emergencies with poor visual prognosis. Iloprost is a stable prostacyclin analogue and has prominent anti-edema, anti-inflammatory, vasodilatory, and antiagregant effects. The main objective of this work was to investigate iloprost as an alternative agent versus hyperbaric oxygen (HBO) in the treatment of CRAO.