Zaprinast and rolipram enhances spatial and emotional memory in the elevated plus maze and passive avoidance tests and diminishes exploratory activity in naive mice.

Creative Commons License

Akar F., MUTLU O., Komsuoglu Celikyurt I., ULAK G., Erden F., BEKTAŞ E., ...More

Medical science monitor basic research, vol.20, pp.105-11, 2014 (Scopus) identifier identifier identifier


Background: Phosphodiesterase (PDE) inhibitors in the central nervous system have been shown to stimulate neuronal functions and increase neurogenesis in Alzheimer disease (AD) patients.