Zaprinast and rolipram enhances spatial and emotional memory in the elevated plus maze and passive avoidance tests and diminishes exploratory activity in naive mice.


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Akar F., MUTLU O., Komsuoglu Celikyurt I., ULAK G., Erden F., BEKTAŞ E., ...More

Medical science monitor basic research, vol.20, pp.105-11, 2014 (Scopus) identifier identifier identifier

Abstract

Background: Phosphodiesterase (PDE) inhibitors in the central nervous system have been shown to stimulate neuronal functions and increase neurogenesis in Alzheimer disease (AD) patients.