The Etiology and Clinical Features of Non-CAH Gonadotropin-Independent Precocious Puberty: A Multicenter Study

Atay, Zeynep; Yesilkaya, Ediz; Erdeve, Senay; DEMİRCİOĞLU, SERAP; Akin, Leyla; EREN, ERDAL; DÖĞER, ESRA; Aycan, Zehra; Abali, Zehra; AKINCI, AYŞEHAN; ŞIKLAR, ZEYNEP; ÖZEN, SAMİM; Kara, Cengiz; Tayfun, Meltem; Sari, Erkan; TÜTÜNCÜLER, FİLİZ; Karabulut, Gulcan; KARAGÜZEL, GÜLAY; Cetinkaya, Semra; Saglam, Halil; Bideci, Aysun; Kurtoglu, Selim; GÜRAN, TÜLAY; Bereket, Abdullah

doi:10.1210/jc.2015-3500

The Etiology and Clinical Features of Non-CAH Gonadotropin-Independent Precocious Puberty: A Multicenter Study

Atay Z., Yesilkaya E., Erdeve S. S., DEMİRCİOĞLU S., Akin L., EREN E., ...Daha Fazla

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, cilt.101, sa.5, ss.1980-1988, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 101 Sayı: 5
Basım Tarihi: 2016
Doi Numarası: 10.1210/jc.2015-3500
Dergi Adı: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1980-1988
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Kocaeli Üniversitesi Adresli: Evet

Özet

Aim: The causes of gonadotropin-independent precocious puberty are diverse, and often have overlapping clinical and biochemical features. With the exception of congenital adrenal hyperplasia (CAH), disorders that cause gonadotropin-independent precocious puberty (GIPP) are uncommon. The literature is devoid of any large-scale studies on the etiologic distribution of GIPP. The aim of this study was to determine the frequency of each etiology in a cohort of patients with GIPP (excluding those with CAH), and to evaluate the clinical and laboratory features of these patients.