Effects of ziprasidone, SCH23390 and SB277011 on spatial memory in the Morris water maze test in naive and MK-801 treated mice


Tanyeri,Tanyeri P., Buyukokuroglu M. E. , Mutlu O. , Ulak G. , Akar F. , Celikyurt I. K. , ...Daha Fazla

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, cilt.138, ss.142-147, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 138
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.pbb.2015.09.014
  • Dergi Adı: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
  • Sayfa Sayıları: ss.142-147

Özet

Introduction: Patients with schizophrenia have cognitive dysfunctions: positive psychotic symptoms are the primary purposes for schizophrenia treatment Improvements in cognitive function should be a characteristic of all newly developed drugs for the treatment of schizophrenia with dementia. Thus, we investigated the effects of the second-generation antipsychotic ziprasidone, dopamine D1 antagonist SCH-23390 and dopamine D3 antagonist SB-277011 on spatial learning and memory.