The effect of combined preinduction thoracic epidural anaesthesia and glucocorticoid administration on perioperative interleukin-10 levels and hyperglycemia. A randomized controlled trial


Kilickan L., YUMUK Z. , Bayindir O.

JOURNAL OF CARDIOVASCULAR SURGERY, cilt.49, ss.87-93, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 49 Konu: 1
  • Basım Tarihi: 2008
  • Dergi Adı: JOURNAL OF CARDIOVASCULAR SURGERY
  • Sayfa Sayıları: ss.87-93

Özet

Aim. Anti-inflammatory cytokines such as interleukin-10 (IL-10) play a key role in the anti-inflammatory cascade after cardiopulmonary bypass (CPB). Even moderate hyperglycemia. can increase mortality/morbidity, stroke, and myocardial infarction after coronary artery bypass grafting (CABG). The purpose of our study was to investigate whether preinduction thoracic epidural anesthesia (TEA) and preinduction glucocorticoid have an effect on perioperative anti-inflainmatory and perioperative hyperglycemia in patients undergoing CABG with CPB.