Parameters of ventricular repolarization in patients with autoimmune hepatitis

Acar B., Yuksel M., Yayla C., Kirbas O., Unal S., Ertem A. G., ...More

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, vol.45, no.4, pp.333-338, 2017 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.5543/tkda.2017.57870
  • Journal Name: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.333-338
  • Keywords: Autoimmune hepatitis, peak and end of T wave interval, QT ratio, TP-E/QT RATIO, C VIRUS-INFECTION, E INTERVAL, TRANSMURAL DISPERSION, CIGARETTE-SMOKING, MARKERS, INDEX, HEART
  • Kocaeli University Affiliated: Yes

Abstract

Objective: Autoimmune hepatitis (AIH) is a liver disorder that affects both children and adults. It is characterized by inflammatory liver histology, elevated transaminase level, circulating nonorgan-specific autoantibodies, and increased level of immunoglobulin G in the absence of known etiology. Ventricular repolarization has been evaluated using T wave and QT interval measurements in patients with hepatic cirrhosis. Ventricular repolarization may be defined using QT interval, QT dispersion, and T wave measurements. Recently, it has been demonstrated that peak and end of the T wave (Tp-e) interval, Tp-e/QT, and Tp-e/corrected QT interval (QTc) ratios can be novel indicators for prediction of ventricular arrhythmias and mortality. In this study, an investigation of ventricular repolarization using Tp-e interval and Tp-e/QT ratio in patients with AIH was performed.