Mast cells and their activations


BAYRAMGÜRLER D. , ODYAKMAZ DEMİRSOY E.

TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY, vol.47, pp.37-40, 2013 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47
  • Publication Date: 2013
  • Doi Number: 10.4274/turkderm.47.s6
  • Title of Journal : TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY
  • Page Numbers: pp.37-40

Abstract

Mast cells which are traditionally known as the major cells of IgE-dependent immediate hypersensitivity reactions are currently recognized to have a role as effector cells in many settings of the both innate and adaptive immunity. Mast cells secrete a wide spectrum of preformed or newly synthesized biologically active mediators with proinflammatory, anti-inflammatory and/or immunosupressive functions, in response to several stimuli. Current knowledge about mast cells and their activation, mast cell mediators, their roles in inflammation and immune system will be discussed in this review.