Therapy in Trigeminal Autonomic Cephalgias

SELEKLER H. M. , Altun S. N.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, vol.47, no.4, pp.279-285, 2010 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 47 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.4274/npa.y5933
  • Page Numbers: pp.279-285


Trigeminal autonomic cephalgias - cluster headache, paroxysmal hemicrania (PH), hemicrania continua (HC) and SUNCT (short-lasting unilateral headache attacks with conjunctival injection and tearing)-are characterized by ipsilateral autonumic features accompanying the unilateral headache. A well-established medical treatment exists for cluster headache. However, problems could arise when treating chronic forms. Main treatment option for PH and HC is indomethacin. Troubles may occur when indomethacin is contrindicated and when replacing it with another agent is needed. Although lamorigine is the most well-known drug in SUNCT treatment, it is not a key drug such as indomethacin. Surgical procedures (e. g. occipital nerve stimulation and hypothalamic stimulation), which have been developed in the last ten years, are promising in the treatment of drug-resistant trigeminal autonomic cephalgia patients. (Archives of Neuropsychiatry 2010; 47: 279-85)