Factors Influencing Parental Consent in a Hypothetical Pediatric Vaccine Trial in a Developing Country Setting: A Questionnaire Study

Serce Ö., Gonen I., Bakir M.

ACCOUNTABILITY IN RESEARCH-POLICIES AND QUALITY ASSURANCE, cilt.22, sa.1, ss.1-13, 2015 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1080/08989621.2014.882779
  • Dergi Adı: ACCOUNTABILITY IN RESEARCH-POLICIES AND QUALITY ASSURANCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.1-13
  • Anahtar Kelimeler: trial, consent, vaccine, child, CLINICAL-RESEARCH, CHILDREN, PARTICIPATION, VOLUNTEER
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

Clinical vaccine trials have been lacking in the pediatric population due to lower consent rate of the parents. We assessed characteristics of the parents, and motives and barriers underlying the decision process. The results of the questionnaire were evaluated by multivariate analysis. Parents who opted in were younger and more often employed than the parents who opted out. The most important motives were receiving detailed information about trial and benefits to human health. The qualified education of medical community and public about the rationale and benefits of trials is essential for opt-in.