Use of Adipose-Derived Mesenchymal Stem Cells to Increase Viability of Composite Grafts

Yucel E., Alagöz M. Ş., Eren G. G., Yaşar E. K., Izmırlı H. H., Duruksu G., ...More

JOURNAL OF CRANIOFACIAL SURGERY, vol.27, pp.1354-1360, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27
  • Publication Date: 2016
  • Doi Number: 10.1097/scs.0000000000002707
  • Journal Name: JOURNAL OF CRANIOFACIAL SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1354-1360
  • Keywords: Composite grafts, neovascularization, stem cell, HYPERBARIC-OXYGEN THERAPY, SKIN FLAP, SURVIVAL, TISSUE, RATS, DIFFERENTIATION
  • Kocaeli University Affiliated: Yes

Abstract

Objective: Chondrocutaneous composite grafts figure among the reconstruction alternatives for alar rim defects resulting from tumor resection and trauma. The major problem with composite grafts is the limited graft survival area. In the present study, the authors aimed to increase the survival area of composite grafts by utilizing the ability of stem cells to promote neovascularization which is crucial in composite graft viability.