Evaluation of left ventricular function and volume in patients with dilated cardiomyopathy: gated myocardial single-photon emission tomography (SPECT) versus echocardiography
ANNALS OF SAUDI MEDICINE, cilt.25, sa.3, ss.198-204, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 25 Sayı: 3
- Basım Tarihi: 2005
- Doi Numarası: 10.5144/0256-4947.2005.198
- Dergi Adı: ANNALS OF SAUDI MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.198-204
- Kocaeli Üniversitesi Adresli: Evet
Özet
BACKGROUND: Left ventricular function, volumes and regional wall. motion provide valuable diagnostic information and are of long-term prognostic importance in patients with dilated cardiomyopathy (DCM). This study was designed to compare the effectiveness of 2D-echocardiography and gated single-photon emission tomography (SPELT) for evaluation of these parameters in patients with DCM. PATIENTS AND METHODS: Gated SPELT and 2D-echocardiography, were performed in 33 patients having DCM. Gated SPELT data; including left ventricular volumes and left ventricular ejection fraction (LVEF), were processed using an automated algorithm. Standard technique was used for 2D-echocardiography. Regional wall motion was evaluated using both modalities and was scored by two independent observers using a 16-segment model with a 5-point scoring system. RESULTS: The overall agreement between the two-imaging modalities for the assessment of regional wall motion was 56% (298/528 segments). With gated SPELT, LVEF, end-diastolic volume (EDV), and end-systolic volume (ESV) were 27 +/- 9%, 217 +/- 77 mL, and 163 +/- 73 mL, respectively, and 30 +/- 8%, 195 +/- 58 mL, and 137 +/- 48 mL with echocardiography. The correlation between gated SPELT and 2D-echocardiography was good (r=0.76, P < 0.01) for the assessment of LVEF The correlation for EDV and ESV were also good, but with wider limits of agreement (r=0.72, P < 0.01 and r=0.73, P < 0.01; respectively) and significantly higher values were obtained with gated SPELT (P < 0.01). CONCLUSIONS: Gated SPELT and 2D-echocardiography correlate well for the assessment of LV function and LV volumes. Like 2D-echocardiography, gated SPELT provides reliable information about LV function and dimension with the additional advantage of perfusion data.