Integrase Strand Transfer Inhibitors (INSTIs) Resistance Mutations in HIV-1 Infected Turkish Patients

Sayan, M.; Gunduz, A.; Ersoz, G.; Inan, A.; Deveci, A.; Ozgur, G.; Sargin, F.; Karagoz, G.; Inci, A.; Inan, D.; Ulcay, A.; Karaoglan, I.; Kaya, S.; Kutlu, S.; Suer, K.; Cagatay, A.; Akalin, H.

doi:10.1080/15284336.2016.1153303

Integrase Strand Transfer Inhibitors (INSTIs) Resistance Mutations in HIV-1 Infected Turkish Patients

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Sayan M., Gunduz A., Ersoz G., Inan A., Deveci A., Ozgur G., ...More

HIV CLINICAL TRIALS, vol.17, no.3, pp.109-113, 2016 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 17 Issue: 3
Publication Date: 2016
Doi Number: 10.1080/15284336.2016.1153303
Journal Name: HIV CLINICAL TRIALS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.109-113
Kocaeli University Affiliated: Yes

Abstract

Objectives: Integrase strand transfer inhibitor (INSTI) is a new class of antiretroviral (ARV) drugs designed to block the action of the integrase viral enzyme, which is responsible for insertation of the HIV-1 genome into the host DNA. The aim of this study was to evaluate for the first time INSTI resistance mutations in Turkish patients.