Which definition should be used to determine colchicine resistance among patients with familial Mediterranean fever?

Erden, A; Batu, ED; Sarı, A; Sönmez, HAFİZE; Armagan, B; Demir, S; Fırat, E; Bilginer, Y; Bilgen, SA; Karadağ, Ö; Kalyoncu, U; Kiraz, S; Ertenli, I; Özen, S; Akdogan, A

Which definition should be used to determine colchicine resistance among patients with familial Mediterranean fever?

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Erden A., Batu E., Sarı A., Sönmez H. E., Armagan B., Demir S., ...More

Clinical and experimental rheumatology, vol.36, pp.97-102, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 36
Publication Date: 2018
Journal Name: Clinical and experimental rheumatology
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.97-102
Kocaeli University Affiliated: Yes

Abstract

Objective. Colchicine is the main therapy for familial Mediterranean fever (FMF); however, 5-10% of patients are colchicine-resistant. There is no standard and validated definition for colchicine resistance. We aimed to compare the existing definitions for colchicine resistance in both adult and paediatric FMF patients to find out the best definition to determine colchicine-resistant patients.