STEM CELL DRUGS - A NEW GENERATION OF BIOPHARMACEUTICALS, vol.25, pp.3-16, 2026 (SCI-Expanded, Scopus)
Common treatments for various diseases are mainly a series of suppressing, modifying, or stimulating drugs that in addition to having unwanted side effects, in the long term with the advancement of the disease, lose their therapeutic efficacy to a large extent. Hence, the treatment of many diseases remains a major challenge in medical research. Among the promising therapeutic strategies that have been introduced in recent years, using mesenchymal stem cells has attracted significant attention. Stem cells are a kind of cells that have the ability to transform to all types of cells in the body. These cells have the ability to regenerate and differentiate into various types of cells, including blood, cardio, nervous, and cartilage cells; they can also be employed to repair various tissues of the body after injury and can be injected into some tissues, the most cells of which are destroyed such as intestine tissues. Transplanting and replacing damaged cells and repairing and fixing defects in a damaged tissue is other abilities of the stem cells. Microvesicles (MVs) are integral components of the cell-to-cell communication network, which releasing from different cells have the ability to progressively become a center of attention in stem cell-based therapy.