Effect of Helicobacter pylori infection on deep vein thrombosis seen in patients with Behçet's disease


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Sentürk O., Özgür O., HÜLAGÜ S., CANTÜRK N. Z., ÇELEBİ A., KARAKAYA A.

East African Medical Journal, cilt.83, sa.1, ss.49-51, 2006 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 83 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.4314/eamj.v83i1.9361
  • Dergi Adı: East African Medical Journal
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.49-51
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Objective: To investigate the role of homocysteine metabolism due to Helicobacter pylori infection on the development of deep vein thrombosis (DVT) in patients with Behcet's disease (BD). Design: Prospective clinical study. Setting: Teaching hospital. Subject: Fifty-five patients with BD divided into groups, with DVT and without DVT, 19 healthy individuals and 18 patients with coronary artery disease (CAD) were enrolled into the study. Interventions: Plasma homocysteine and Hp seropositivity were determined. Results: There was significant Hp positivity in all groups (p > 0.05). Homocysteine levels were not significantly different for each group except patients with CAD (p > 0.05). Conclusion: There was no difference for frequency of Hp infection in all groups. We conclude that Hp does not influence DVT seen in BD via homocysteine metabolism, but the methinnin-loading test would be appropriate for enlighting patients whose fasting plasma homocysteine levels are found to be normal.