Protective effect of a nuclear factor kappa B inhibitor, pyrolidium dithiocarbamate, in the kidney of rats with nephrolithiasis induced by ethylene glycol

Tugcu V., Ozbek E., Kemahli E., Cekmen M. B., Caner N., Somay A., ...More

JOURNAL OF ENDOUROLOGY, vol.21, no.9, pp.1097-1106, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 9
  • Publication Date: 2007
  • Doi Number: 10.1089/end.2007.0074
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1097-1106
  • Kocaeli University Affiliated: No


Purpose: To study the protective effects of a selective nuclear factor kappa B (NF-kappa B) inhibitor, pyrolidium dithiocarbamate (PDTC), on ethylene glycol-induced crystal deposition in the renal tubules, renal toxicity, as well as inducible nitric oxide synthase (iNOS) and NF-kappa B activities in rat kidneys.