Protective effect of a nuclear factor kappa B inhibitor, pyrolidium dithiocarbamate, in the kidney of rats with nephrolithiasis induced by ethylene glycol

Tugcu, Volkan; Ozbek, Emin; Kemahli, Eray; Cekmen, Mustafa; Caner, Nazli; Somay, Adnan; Erturkuner, Pelin; Seckin, Ismail; Demir, Cennet; Altug, Tuncay; Tasci, Ali

doi:10.1089/end.2007.0074

Protective effect of a nuclear factor kappa B inhibitor, pyrolidium dithiocarbamate, in the kidney of rats with nephrolithiasis induced by ethylene glycol

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Tugcu V., Ozbek E., Kemahli E., Cekmen M. B., Caner N., Somay A., ...More

JOURNAL OF ENDOUROLOGY, vol.21, no.9, pp.1097-1106, 2007 (SCI-Expanded)

Publication Type: Article / Article
Volume: 21 Issue: 9
Publication Date: 2007
Doi Number: 10.1089/end.2007.0074
Journal Name: JOURNAL OF ENDOUROLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1097-1106
Kocaeli University Affiliated: No

Abstract

Purpose: To study the protective effects of a selective nuclear factor kappa B (NF-kappa B) inhibitor, pyrolidium dithiocarbamate (PDTC), on ethylene glycol-induced crystal deposition in the renal tubules, renal toxicity, as well as inducible nitric oxide synthase (iNOS) and NF-kappa B activities in rat kidneys.