Akademik Veri Yönetim Sistemi
6TH ANKARA INTERNATIONAL CONGRESS ON SCIENTIFIC RESEARCH, Ankara, Türkiye, 01 Nisan 2022, cilt.1, ss.80-83
Ovarian epithelial tumors are one of most frequently encountered gynecological specimens
sent to pathology laboratories intraoperatively.Preoperative diagnosis of an ovarian mass is
limited due to low sensitivity and specificity imaging studies,serum markers.Therefore,
intraoperative frozen section evaluation, oophorectomy or limited surgical staging for
borderline tumors in younger patients is crucial to preserve necessary surgical scope, ie
fertility or to determine comprehensive staging procedure for ovarian carcinomas.
Our aim in this study is to present rate of agreement between definite histopathological
results of sections obtained by intraoperative examination and postoperative paraffinization in
cases diagnosed with borderline ovarian tumor,undergoing oophorectomy for 4.5 years in our
department.Reports of cases with ovarian mass, clinical-radiologically suspected malignancy,
and intraoperative examination requested between May 2017 and December 2021 were
reviewed retrospectively.A total of 80 patients with ovarian mass were diagnosed with
borderline tumor in our department.There were 52 patients who underwent intraoperative
examination.The mean tumor diameter was 11.3 cm. 45 patients were correctly diagnosed
under frozen conditions.The sensitivity of intraoperative examination in predicting
malignancy was calculated as 86.5%. 71.4% of those who were misdiagnosed were cases
with borderline mucinous tumors.A large number of samples were taken from post-frozen
materials and paraffinized sections were examined.53.8% of these neoplasms were diagnosed
as borderline serous tumor, 8.9% of borderline mucinous tumor, 11.5% of them as borderline
seromucinous tumor,5.8% of them as borderline endometrioid tumor.Although intraoperative
frozen section diagnosis seems to be an accurate technique for histopathological diagnosis of
ovarian tumors,frozen section evaluation of ovarian borderline tumors continues to pose an
important diagnostic challenge for pathologists.Large-diameter tissues, particularly mucinous
subtype, are limitations to use of frozen sections.Regular reassessment or consultation
regarding disagreements between frozen section diagnosis and final permanent paraffin
diagnosis can be undertaken by both surgeons and pathologists to determine the most
appropriate intraoperative management for patients with ovarian tumors.