Effects of Epirubicin and Cisplatin Against 4T1 Breast Cancer Cells are Enhanced by Myrtucommulone-A


Izgia K., Iskender B. , Sakalar C., Arslanhan A., Yuksek E. H. , Hizar E., ...More

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.17, no.3, pp.404-414, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.2174/1871520616666160404110543
  • Title of Journal : ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Page Numbers: pp.404-414
  • Keywords: Myrtucommulone A, Cancer, Cisplatin, Epirubicin, 4T1, Cancer resistance, GENE-EXPRESSION PATTERNS, NF-KAPPA-B, BCL-W, INDUCED APOPTOSIS, TRAIL-RESISTANCE, PROTEIN-LEVELS, P53, FAMILY, ACTIVATION, DEATH

Abstract

Background: The number of cancer cases around the world has increased according to the World Health Organization (WHO) reports, nearly 14 million new cases and 8.2 million cancer associated mortalities have been reported in 2012. Chemotherapeutic resistance is a major problematic issue in the management of patients with breast tumor.