A Putative Functional Variant Within the UBAC2 Gene Is Associated With Increased Risk of Behcet's Disease


Sawalha A. H. , HUGHES T., NADİG A., Yilmaz V., AKSU K., KESER G., et al.

ARTHRITIS AND RHEUMATISM, cilt.63, ss.3607-3612, 2011 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 63 Konu: 11
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1002/art.30604
  • Dergi Adı: ARTHRITIS AND RHEUMATISM
  • Sayfa Sayısı: ss.3607-3612

Özet

Objective. Using a genome-wide association scan and DNA pooling, we previously identified 5 novel genetic susceptibility loci for Behc,et's disease. We undertook this study to establish the genetic effect within the UBAC2 gene, in the course of which we replicated this genetic association and identified a functional variant within this locus.