A Putative Functional Variant Within the UBAC2 Gene Is Associated With Increased Risk of Behcet's Disease

Sawalha, Amr; HUGHES, Travis; NADİG, Ajay; Yilmaz, Vuslat; AKSU, KENAN; KESER, GÖKHAN; ÇEFLE, AYŞE; YAZICI, AYTEN; ERGEN, Andac; Alarcon-Riquelme, Marta; SALVARANİ, Carlo; CASALİ, Bruno; Direskeneli, Haner; Saruhan-Direskeneli, Guher

doi:10.1002/art.30604

A Putative Functional Variant Within the UBAC2 Gene Is Associated With Increased Risk of Behcet's Disease

Sawalha A. H., HUGHES T., NADİG A., Yilmaz V., AKSU K., KESER G., ...Daha Fazla

ARTHRITIS AND RHEUMATISM, cilt.63, sa.11, ss.3607-3612, 2011 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 63 Sayı: 11
Basım Tarihi: 2011
Doi Numarası: 10.1002/art.30604
Dergi Adı: ARTHRITIS AND RHEUMATISM
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.3607-3612
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Kocaeli Üniversitesi Adresli: Evet

Özet

Objective. Using a genome-wide association scan and DNA pooling, we previously identified 5 novel genetic susceptibility loci for Behc,et's disease. We undertook this study to establish the genetic effect within the UBAC2 gene, in the course of which we replicated this genetic association and identified a functional variant within this locus.