A Putative Functional Variant Within the UBAC2 Gene Is Associated With Increased Risk of Behcet's Disease

Creative Commons License

Sawalha A. H., HUGHES T., NADİG A., Yilmaz V., AKSU K., KESER G., ...Daha Fazla

ARTHRITIS AND RHEUMATISM, cilt.63, sa.11, ss.3607-3612, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 11
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1002/art.30604
  • Dergi Adı: ARTHRITIS AND RHEUMATISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3607-3612
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Objective. Using a genome-wide association scan and DNA pooling, we previously identified 5 novel genetic susceptibility loci for Behc,et's disease. We undertook this study to establish the genetic effect within the UBAC2 gene, in the course of which we replicated this genetic association and identified a functional variant within this locus.