Effect of rosiglitazone on insulin resistance, C-reactive protein and endothelial function in non-obese young women with polycystic ovary symdrome


Creative Commons License

Tarkun I., Cetinarslan B. , Turemen E., Sahin T., Canturk Z., Komsuoglu B.

EUROPEAN JOURNAL OF ENDOCRINOLOGY, cilt.153, ss.115-121, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 153 Konu: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1530/eje.1.01948
  • Dergi Adı: EUROPEAN JOURNAL OF ENDOCRINOLOGY
  • Sayfa Sayıları: ss.115-121

Özet

Objective: Women with polycystic ovary syndrome (PCOS) exhibit elevated levels of serum C-reactive protein (CRP) and impaired endothelium dysfunction which arc directly correlated with insulin resistance. Because rosiglitazone improves insulin sensitivity, we tested whether rosiglitazone treatment ameliorates high-sensitivity (hs)CRP levels and endothelial dysfunction in these patients.