Effects of caffeine on placental total nitrite concentration: A 21-day, vehicle-controlled study in rats

Alasehirli, B; Cekmen, M; Nacak, M; Balat, A

doi:10.1016/j.curtheres.2005.04.003

Effects of caffeine on placental total nitrite concentration: A 21-day, vehicle-controlled study in rats

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Alasehirli B., Cekmen M., Nacak M., Balat A.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, vol.66, no.2, pp.130-137, 2005 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 66 Issue: 2
Publication Date: 2005
Doi Number: 10.1016/j.curtheres.2005.04.003
Journal Name: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.130-137
Kocaeli University Affiliated: No

Abstract

Background: Nitric oxide (NO) is a potent vasodilator that might have an important role in the modulation of maternal and fetal vascular tone during pregnancy. The effects of caffeine intake on maternal and fetal hemodynamic properties during pregnancy have been investigated in several human and animal studies. However, based on a literature search, there has been no study of placental total nitrite (a stable product of NO) concentration (PTNC) in pregnant humans or rats given caffeine.