Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial

Winchester, Danyelle; Gurel, BORA; Till, Cathee; Goodman, Phyllis; Tangen, Catherine; Santella, Regina; Johnson-Pais, Teresa; Leach, Robin; Thompson, Ian; Xu, Jianfeng; Zheng, S.; Lucia, M.; Lippman, Scott; Parnes, Howard; Isaacs, William; Drake, Charles; De Marzo, Angelo; Platz, Elizabeth

doi:10.1002/pros.23147

Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial

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Winchester D. A. , Gurel B. , Till C., Goodman P. J. , Tangen C. M. , Santella R. M. , ...More

PROSTATE, vol.76, no.6, pp.565-574, 2016 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 76 Issue: 6
Publication Date: 2016
Doi Number: 10.1002/pros.23147
Journal Name: PROSTATE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.565-574
Kocaeli University Affiliated: Yes

Abstract

BACKGROUNDWe previously reported that both intraprostatic inflammation and SNPs in genes involved in the immune response are associated with prostate cancer risk and disease grade. In the present study, we evaluated the association between these SNPs and intraprostatic inflammation in men without a prostate cancer diagnosis.