Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial


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Winchester D. A., Gurel B., Till C., Goodman P. J., Tangen C. M., Santella R. M., ...More

PROSTATE, vol.76, no.6, pp.565-574, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.1002/pros.23147
  • Journal Name: PROSTATE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.565-574
  • Kocaeli University Affiliated: Yes

Abstract

BACKGROUNDWe previously reported that both intraprostatic inflammation and SNPs in genes involved in the immune response are associated with prostate cancer risk and disease grade. In the present study, we evaluated the association between these SNPs and intraprostatic inflammation in men without a prostate cancer diagnosis.