Hypogonadism in Prader-Willi syndrome from birth to adulthood: a 28-year experience in a single centre

Kherra S., Paterson W. F., Cizmecioglu F. M., Jones J. H., Kourime M., Elsedfy H. H., ...More

ENDOCRINE CONNECTIONS, vol.10, no.9, pp.1134-1146, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 9
  • Publication Date: 2021
  • Doi Number: 10.1530/ec-21-0277
  • Journal Name: ENDOCRINE CONNECTIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1134-1146
  • Keywords: Prader-Willi syndrome, central hypogonadism, primary hypogonadism, cryptorchidism, orchidopexy, pelvic ultrasound, gonadotrophins, human chorionic gonadotrophin, puberty, oestrogen therapy, testosterone therapy, BODY-COMPOSITION, BOYS, DIAGNOSIS, INFANCY, GIRLS, AGE
  • Kocaeli University Affiliated: Yes

Abstract

Background: Hypogonadism is a key feature of Prader-Willi syndrome (PWS) but clear strategies for hormone replacement are lacking.