Comparison of Mesenchymal Stem Cells Isolated From Pulp and Periodontal Ligament

Hakki S. S., Kayis S. A., Hakki E. E., Bozkurt S. B., Duruksu G., Ünal Z. S., ...Daha Fazla

JOURNAL OF PERIODONTOLOGY, cilt.86, ss.283-291, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 86
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1902/jop.2014.140257
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.283-291
  • Anahtar Kelimeler: Cell biology, differentiation, gene expression, mesenchymal stem cell, molecular biology, regenerative medicine, HUMAN DENTAL-PULP, STROMAL CELLS, BONE REGENERATION, TISSUE, DIFFERENTIATION, CAPACITY, THERAPY, UTILITY, TEETH
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Background: Cell-based therapy using mesenchymal stem cells (MSCs) seems promising to obtain regeneration of dental tissues. A comparison of tissue sources, including periodontal ligament (PDL) versus pulp (P), could provide critical information to select an appropriate MSC population for designing predictable regenerative therapies. The purpose of this study is to compare the proliferation and stemness and the MSC-specific and mineralized tissue-specific gene expression of P-MSCs and PDL-MSCs.